Application Notes for Centrifugal Partition Chromatography
LiLiChro
Explore real purification examples using centrifugal partition chromatography from pharmaceutical compounds and ionisable lipids to natural extracts, food-grade materials, and method development studies.
Looking for a scalable alternative to solid-phase chromatography?
Explore LiLiChro’s liquid-liquid chromatography application notes and see how centrifugal partition chromatography can support compound purification, molecule separation, natural product isolation, cannabinoid purification, and pharma R&D workflows without a solid stationary phase.
Short teaser:
Cyclosporine pre-purification with CPC: see how support-free liquid-liquid chromatography can help separate crude cyclosporine fractions before final polishing, with controlled recovery of apolar impurities, the main product fraction, and polar post-fractions.
Best for:
Pharmaceutical R&D teams, API purification specialists, Purification scientists, Process development teams, CPC and liquid-liquid chromatography users, Labs evaluating alternatives to preparative HPLC or flash chromatography
Short teaser:
See how CPC can remove chlorophyll, alkaloids, and other organically soluble compounds from crude vegetable leaf extracts — helping produce cleaner water-soluble protein fractions through scalable liquid-liquid chromatography.
Best for:
Plant protein purification teams, Food and nutraceutical R&D, Natural product purification specialists, Bioprocess and downstream processing teams, Labs working with crude vegetable leaf extracts, Teams evaluating CPC for chlorophyll removal or pigment remediation
Short teaser:
Explore how CPC can support ionisable lipid purification under water-free conditions. This application note highlights a liquid-liquid chromatography workflow for separating hydrophobic lipid compounds where conventional aqueous systems may not be suitable.
Best for:
Lipid nanoparticle and drug delivery R&D teams, Pharmaceutical purification scientists, Biotech process development teams, Ionisable lipid and hydrophobic compound specialists, Labs working with water-sensitive purification workflows, Teams evaluating CPC for pharmaceutical compound purification
Short teaser:
See how CPC can support fast purification of flavoring materials from complex biological samples using support-free liquid-liquid chromatography — a practical workflow for isolating valuable aroma or flavor compounds from challenging natural matrices.
Best for:
Flavor and fragrance R&D teams, Natural product purification specialists, Food and beverage ingredient developers, Biological sample preparation teams, Nutraceutical and botanical extract researchers, Labs evaluating CPC for complex natural matrices
Short teaser:
See how miniLiLi performs in a column loading test using methyl and ethyl paraben. This application note supports liquid-liquid chromatography method development by showing how sample loading affects separation performance, resolution, and practical workflow setup.
Best for:
CPC method development teams, Analytical and preparative chromatography labs, Purification scientists, R&D teams evaluating miniLiLi, Labs planning scale-up from miniLiLi to larger CPC systems, Teams testing sample loading and separation performance
Short teaser:
See how CPC can support EGCG purification from green tea polyphenol extract using support-free liquid-liquid chromatography — a practical workflow for isolating high-value natural compounds from complex botanical matrices.
Best for:
Natural product purification teams, Nutraceutical R&D specialists, Botanical extract researchers, Food-grade compound purification teams, Polyphenol and antioxidant researchers, Labs evaluating CPC for plant extract purification
Short teaser:
Cyclosporine pre-purification with CPC: see how support-free liquid-liquid chromatography can help separate crude cyclosporine fractions before final polishing, with controlled recovery of apolar impurities, the main product fraction, and polar post-fractions.
Best for:
Pharmaceutical R&D teams, API purification specialists, Purification scientists, Process development teams, CPC and liquid-liquid chromatography users, Labs evaluating alternatives to preparative HPLC or flash chromatography
Short teaser:
Explore how CPC can support ionisable lipid purification under water-free conditions. This application note highlights a liquid-liquid chromatography workflow for separating hydrophobic lipid compounds where conventional aqueous systems may not be suitable.
Best for:
Lipid nanoparticle and drug delivery R&D teams, Pharmaceutical purification scientists, Biotech process development teams, Ionisable lipid and hydrophobic compound specialists, Labs working with water-sensitive purification workflows, Teams evaluating CPC for pharmaceutical compound purification
Short teaser:
See how CPC can remove chlorophyll, alkaloids, and other organically soluble compounds from crude vegetable leaf extracts — helping produce cleaner water-soluble protein fractions through scalable liquid-liquid chromatography.
Best for:
Plant protein purification teams, Food and nutraceutical R&D, Natural product purification specialists, Bioprocess and downstream processing teams, Labs working with crude vegetable leaf extracts, Teams evaluating CPC for chlorophyll removal or pigment remediation
Short teaser:
See how CPC can support fast purification of flavoring materials from complex biological samples using support-free liquid-liquid chromatography — a practical workflow for isolating valuable aroma or flavor compounds from challenging natural matrices.
Best for:
Flavor and fragrance R&D teams, Natural product purification specialists, Food and beverage ingredient developers, Biological sample preparation teams, Nutraceutical and botanical extract researchers, Labs evaluating CPC for complex natural matrices
Short teaser:
See how CPC can support EGCG purification from green tea polyphenol extract using support-free liquid-liquid chromatography — a practical workflow for isolating high-value natural compounds from complex botanical matrices.
Best for:
Natural product purification teams, Nutraceutical R&D specialists, Botanical extract researchers, Food-grade compound purification teams, Polyphenol and antioxidant researchers, Labs evaluating CPC for plant extract purification
Short teaser:
See how miniLiLi performs in a column loading test using methyl and ethyl paraben. This application note supports liquid-liquid chromatography method development by showing how sample loading affects separation performance, resolution, and practical workflow setup.
Best for:
CPC method development teams, Analytical and preparative chromatography labs, Purification scientists, R&D teams evaluating miniLiLi, Labs planning scale-up from miniLiLi to larger CPC systems, Teams testing sample loading and separation performance